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The Minimal Autoinhibited Unit of the Guanine Nucleotide Exchange Factor Intersectin
Intersectin-1L is a member of the Dbl homology (DH) domain guanine nucleotide exchange factors (GEF) which control Rho-family GTPase signaling. Intersectin-1L is a GEF that is specific for Cdc42. It plays an important role in endocytosis, and is regulated by several partners including the actin regu...
Autores principales: | Ahmad, K. Farid, Lim, Wendell A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892021/ https://www.ncbi.nlm.nih.gov/pubmed/20585582 http://dx.doi.org/10.1371/journal.pone.0011291 |
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