A Femtomol Range FRET Biosensor Reports Exceedingly Low Levels of Cell Surface Furin: Implications for the Processing of Anthrax Protective Antigen

Furin, a specialized endoproteinase, transforms proproteins into biologically active proteins. Furin function is important for normal cells and also in multiple pathologies including malignancy and anthrax. Furin is believed to cycle between the Golgi compartment and the cell surface. Processing of...

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Detalles Bibliográficos
Autores principales: Gawlik, Katarzyna, Remacle, Albert G., Shiryaev, Sergey A., Golubkov, Vladislav S., Ouyang, Mingxing, Wang, Yingxiao, Strongin, Alex Y.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892035/
https://www.ncbi.nlm.nih.gov/pubmed/20585585
http://dx.doi.org/10.1371/journal.pone.0011305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892035/
https://www.ncbi.nlm.nih.gov/pubmed/20585585
http://dx.doi.org/10.1371/journal.pone.0011305

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