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A Femtomol Range FRET Biosensor Reports Exceedingly Low Levels of Cell Surface Furin: Implications for the Processing of Anthrax Protective Antigen
Furin, a specialized endoproteinase, transforms proproteins into biologically active proteins. Furin function is important for normal cells and also in multiple pathologies including malignancy and anthrax. Furin is believed to cycle between the Golgi compartment and the cell surface. Processing of...
Autores principales: | Gawlik, Katarzyna, Remacle, Albert G., Shiryaev, Sergey A., Golubkov, Vladislav S., Ouyang, Mingxing, Wang, Yingxiao, Strongin, Alex Y. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892035/ https://www.ncbi.nlm.nih.gov/pubmed/20585585 http://dx.doi.org/10.1371/journal.pone.0011305 |
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