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5-HT(1A) receptor blockade reverses GABA(A) receptor α(3) subunit-mediated anxiolytic effects on stress-induced hyperthermia
RATIONALE: Stress-related disorders are associated with dysfunction of both serotonergic and GABAergic pathways, and clinically effective anxiolytics act via both neurotransmitter systems. As there is evidence that the GABA(A) and the serotonin receptor system interact, a serotonergic component in t...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892061/ https://www.ncbi.nlm.nih.gov/pubmed/20535452 http://dx.doi.org/10.1007/s00213-010-1895-7 |