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Inflammasome and IL-1β-Mediated Disorders

The NLRP3 inflammasome is an intracellular complex that regulates the release of proinflammatory cytokines such as interleukin-1β in response to exogenous pathogens and endogenous danger signals. Evidence from studies involving human genetics, human ex vivo mononuclear cell responses, and in vivo an...

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Detalles Bibliográficos
Autores principales: Hoffman, Hal M., Wanderer, Alan A.
Formato: Texto
Lenguaje:English
Publicado: Current Science Inc. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892083/
https://www.ncbi.nlm.nih.gov/pubmed/20425006
http://dx.doi.org/10.1007/s11882-010-0109-z