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Inflammasome and IL-1β-Mediated Disorders
The NLRP3 inflammasome is an intracellular complex that regulates the release of proinflammatory cytokines such as interleukin-1β in response to exogenous pathogens and endogenous danger signals. Evidence from studies involving human genetics, human ex vivo mononuclear cell responses, and in vivo an...
Autores principales: | Hoffman, Hal M., Wanderer, Alan A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Current Science Inc.
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892083/ https://www.ncbi.nlm.nih.gov/pubmed/20425006 http://dx.doi.org/10.1007/s11882-010-0109-z |
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