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Cracking pre-40S ribosomal subunit structure by systematic analyses of RNA–protein cross-linking

Understanding of eukaryotic ribosome synthesis has been slowed by a lack of structural data for the pre-ribosomal particles. We report rRNA-binding sites for six late-acting 40S ribosome synthesis factors, three of which cluster around the 3′ end of the 18S rRNA in model 3D structures. Enp1 and Ltv1...

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Detalles Bibliográficos
Autores principales: Granneman, Sander, Petfalski, Elisabeth, Swiatkowska, Agata, Tollervey, David
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892368/
https://www.ncbi.nlm.nih.gov/pubmed/20453830
http://dx.doi.org/10.1038/emboj.2010.86