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Cracking pre-40S ribosomal subunit structure by systematic analyses of RNA–protein cross-linking
Understanding of eukaryotic ribosome synthesis has been slowed by a lack of structural data for the pre-ribosomal particles. We report rRNA-binding sites for six late-acting 40S ribosome synthesis factors, three of which cluster around the 3′ end of the 18S rRNA in model 3D structures. Enp1 and Ltv1...
Autores principales: | Granneman, Sander, Petfalski, Elisabeth, Swiatkowska, Agata, Tollervey, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892368/ https://www.ncbi.nlm.nih.gov/pubmed/20453830 http://dx.doi.org/10.1038/emboj.2010.86 |
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