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One-hit wonders of genomic instability

Recent data show that cells from many cancers exhibit massive chromosome instability. The traditional view is that the gradual accumulation of mutations in genes involved in transcriptional regulation and cell cycle controls results in tumor development. This, however, does not exclude the possibili...

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Detalles Bibliográficos
Autor principal: Strunnikov, Alexander V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892438/
https://www.ncbi.nlm.nih.gov/pubmed/20482869
http://dx.doi.org/10.1186/1747-1028-5-15