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One-hit wonders of genomic instability
Recent data show that cells from many cancers exhibit massive chromosome instability. The traditional view is that the gradual accumulation of mutations in genes involved in transcriptional regulation and cell cycle controls results in tumor development. This, however, does not exclude the possibili...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892438/ https://www.ncbi.nlm.nih.gov/pubmed/20482869 http://dx.doi.org/10.1186/1747-1028-5-15 |