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Network properties of human disease genes with pleiotropic effects
BACKGROUND: The ability of a gene to cause a disease is known to be associated with the topological position of its protein product in the molecular interaction network. Pleiotropy, in human genetic diseases, refers to the ability of different mutations within the same gene to cause different pathol...
Autores principales: | Chavali, Sreenivas, Barrenas, Fredrik, Kanduri, Kartiek, Benson, Mikael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892460/ https://www.ncbi.nlm.nih.gov/pubmed/20525321 http://dx.doi.org/10.1186/1752-0509-4-78 |
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