Postnatal PPARδ Activation and Myostatin Inhibition Exert Distinct yet Complimentary Effects on the Metabolic Profile of Obese Insulin-Resistant Mice

BACKGROUND: Interventions for T2DM have in part aimed to mimic exercise. Here, we have compared the independent and combined effects of a PPARδ agonist and endurance training mimetic (GW501516) and a myostatin antibody and resistance training mimetic (PF-879) on metabolic and performance outcomes in...

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Detalles Bibliográficos
Autores principales: Bernardo, Barbara L., Wachtmann, Timothy S., Cosgrove, Patricia G., Kuhn, Max, Opsahl, Alan C., Judkins, Kyle M., Freeman, Thomas B., Hadcock, John R., LeBrasseur, Nathan K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892469/
https://www.ncbi.nlm.nih.gov/pubmed/20593012
http://dx.doi.org/10.1371/journal.pone.0011307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892469/
https://www.ncbi.nlm.nih.gov/pubmed/20593012
http://dx.doi.org/10.1371/journal.pone.0011307

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