Antagonistic Changes in Sensitivity to Antifungal Drugs by Mutations of an Important ABC Transporter Gene in a Fungal Pathogen

Fungal pathogens can be lethal, especially among immunocompromised populations, such as patients with AIDS and recipients of tissue transplantation or chemotherapy. Prolonged usage of antifungal reagents can lead to drug resistance and treatment failure. Understanding mechanisms that underlie drug r...

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Detalles Bibliográficos
Autores principales: Guan, Wenjun, Jiang, Huifeng, Guo, Xiaoxian, Mancera, Eugenio, Xu, Lin, Li, Yudong, Steinmetz, Lars, Li, Yongquan, Gu, Zhenglong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892482/
https://www.ncbi.nlm.nih.gov/pubmed/20593017
http://dx.doi.org/10.1371/journal.pone.0011309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892482/
https://www.ncbi.nlm.nih.gov/pubmed/20593017
http://dx.doi.org/10.1371/journal.pone.0011309

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