Insulin Degrading Enzyme Induces a Conformational Change in Varicella-Zoster Virus gE, and Enhances Virus Infectivity and Stability

Varicella-zoster virus (VZV) glycoprotein E (gE) is essential for virus infectivity and binds to a cellular receptor, insulin-degrading enzyme (IDE), through its unique amino terminal extracellular domain. Previous work has shown IDE plays an important role in VZV infection and virus cell-to-cell sp...

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Detalles Bibliográficos
Autores principales: Li, Qingxue, Ali, Mir A., Wang, Kening, Sayre, Dean, Hamel, Frederick G., Fischer, Elizabeth R., Bennett, Robert G., Cohen, Jeffrey I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892511/
https://www.ncbi.nlm.nih.gov/pubmed/20593027
http://dx.doi.org/10.1371/journal.pone.0011327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892511/
https://www.ncbi.nlm.nih.gov/pubmed/20593027
http://dx.doi.org/10.1371/journal.pone.0011327

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