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Variations of X Chromosome Inactivation Occur in Early Passages of Female Human Embryonic Stem Cells

X chromosome inactivation (XCI) is a dosage compensation mechanism essential for embryonic development and cell physiology. Human embryonic stem cells (hESCs) derived from inner cell mass (ICM) of blastocyst stage embryos have been used as a model system to understand XCI initiation and maintenance....

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Detalles Bibliográficos
Autores principales: Dvash, Tamar, Lavon, Neta, Fan, Guoping
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892515/
https://www.ncbi.nlm.nih.gov/pubmed/20593031
http://dx.doi.org/10.1371/journal.pone.0011330