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Variations of X Chromosome Inactivation Occur in Early Passages of Female Human Embryonic Stem Cells
X chromosome inactivation (XCI) is a dosage compensation mechanism essential for embryonic development and cell physiology. Human embryonic stem cells (hESCs) derived from inner cell mass (ICM) of blastocyst stage embryos have been used as a model system to understand XCI initiation and maintenance....
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892515/ https://www.ncbi.nlm.nih.gov/pubmed/20593031 http://dx.doi.org/10.1371/journal.pone.0011330 |