Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination

Primary loss and dysfunction of astrocytes may trigger demyelination, as seen in neuromyelitis optica, an inflammatory disease of the central nervous system. In most patients affected by this disease, injury to astrocytes is initiated by the action of autoantibodies targeting aquaporin 4 (AQP-4), a...

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Detalles Bibliográficos
Autores principales: Sharma, Rakhi, Fischer, Marie-Therese, Bauer, Jan, Felts, Paul A., Smith, Kenneth J., Misu, Tatsuro, Fujihara, Kazuo, Bradl, Monika, Lassmann, Hans
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892605/
https://www.ncbi.nlm.nih.gov/pubmed/20532539
http://dx.doi.org/10.1007/s00401-010-0704-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892605/
https://www.ncbi.nlm.nih.gov/pubmed/20532539
http://dx.doi.org/10.1007/s00401-010-0704-z

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