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Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination
Primary loss and dysfunction of astrocytes may trigger demyelination, as seen in neuromyelitis optica, an inflammatory disease of the central nervous system. In most patients affected by this disease, injury to astrocytes is initiated by the action of autoantibodies targeting aquaporin 4 (AQP-4), a...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892605/ https://www.ncbi.nlm.nih.gov/pubmed/20532539 http://dx.doi.org/10.1007/s00401-010-0704-z |