CYP1A1 gene polymorphisms as a risk factor for pterygium

PURPOSE: Both cytochrome P4501A1 (CYP1A1) and glutathione S-transferase M1 (GSTM1) have been demonstrated to be involved in the metabolism of polycyclic aromatic hydrocarbons (PAHs). BaP 7,8-diol 9,10-epoxide (BPDE), an ultimate metabolite of benzo(a)pyrene (BaP), attacks deoxyguanosine to form a BP...

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Detalles Bibliográficos
Autores principales: Young, Chi-Hsien, Lo, Yu-Lun, Tsai, Yi-Yu, Shih, Tung-Sheng, Lee, Huei, Cheng, Ya-Wen
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893055/
https://www.ncbi.nlm.nih.gov/pubmed/20596254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893055/
https://www.ncbi.nlm.nih.gov/pubmed/20596254

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