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A new strategy for isolating genes controlling dosage compensation in Drosophila using a simple epigenetic mosaic eye phenotype

BACKGROUND: The Drosophila Male Specific Lethal (MSL) complex contains chromatin modifying enzymes and non-coding roX RNA. It paints the male X at hundreds of bands where it acetylates histone H4 at lysine 16. This epigenetic mark increases expression from the single male X chromosome approximately...

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Detalles Bibliográficos
Autores principales: Prabhakaran, Mahalakshmi, Kelley, Richard L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893135/
https://www.ncbi.nlm.nih.gov/pubmed/20537125
http://dx.doi.org/10.1186/1741-7007-8-80