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A novel nucleotide insertion in S gene of hepatitis B virus in a chronic carrier

Hepatitis B virus DNA was extracted from serum of a chronic carrier and polymerase chain reaction was performed on S gene. Direct sequencing showed a variant HBsAg with additional 4-amino acid insertion, and clone sequencing confirmed the mixture of variant HBsAg and wildtype HBsAg. Of 16 clones wit...

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Detalles Bibliográficos
Autores principales: Tong, Wenbin, Sun, Li, He, Jilan, He, Shusen, Du, Fei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893152/
https://www.ncbi.nlm.nih.gov/pubmed/20492719
http://dx.doi.org/10.1186/1743-422X-7-104