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Identifying and Seeing beyond Multiple Sequence Alignment Errors Using Intra-Molecular Protein Covariation
BACKGROUND: There is currently no way to verify the quality of a multiple sequence alignment that is independent of the assumptions used to build it. Sequence alignments are typically evaluated by a number of established criteria: sequence conservation, the number of aligned residues, the frequency...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893159/ https://www.ncbi.nlm.nih.gov/pubmed/20596526 http://dx.doi.org/10.1371/journal.pone.0011082 |