Identifying and Seeing beyond Multiple Sequence Alignment Errors Using Intra-Molecular Protein Covariation

BACKGROUND: There is currently no way to verify the quality of a multiple sequence alignment that is independent of the assumptions used to build it. Sequence alignments are typically evaluated by a number of established criteria: sequence conservation, the number of aligned residues, the frequency...

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Detalles Bibliográficos
Autores principales: Dickson, Russell J., Wahl, Lindi M., Fernandes, Andrew D., Gloor, Gregory B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893159/
https://www.ncbi.nlm.nih.gov/pubmed/20596526
http://dx.doi.org/10.1371/journal.pone.0011082

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