Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases

Type II DNA topoisomerases are ubiquitous enzymes with essential functions in DNA replication, recombination and transcription. They change DNA topology by forming a transient covalent cleavage complex with a gate-DNA duplex that allows transport of a second duplex though the gate. Despite its biolo...

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Detalles Bibliográficos
Autores principales: Laponogov, Ivan, Pan, Xiao-Su, Veselkov, Dennis A., McAuley, Katherine E., Fisher, L. Mark, Sanderson, Mark R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893164/
https://www.ncbi.nlm.nih.gov/pubmed/20596531
http://dx.doi.org/10.1371/journal.pone.0011338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893164/
https://www.ncbi.nlm.nih.gov/pubmed/20596531
http://dx.doi.org/10.1371/journal.pone.0011338

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