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RNAi-mediated silencing of CD147 inhibits tumor cell proliferation, invasion and increases chemosensitivity to cisplatin in SGC7901 cells in vitro

BACKGROUND: CD147 is a widely distributed cell surface glycoprotein that belongs to the Ig superfamily. CD147 has been implicated in numerous physiological and pathological activities. Enriched on the surface of many tumor cells, CD147 promotes tumor growth, invasion, metastasis and angiogenesis and...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Xu, Yong-Fei, He, Bang-Shun, Pan, Yu-Qin, Zhang, Li-Rong, Zhu, Chan, Qu, Li-Li, Wang, Shu-Kui
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893454/
https://www.ncbi.nlm.nih.gov/pubmed/20525232
http://dx.doi.org/10.1186/1756-9966-29-61