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LPS-induced IL-8 activation in human intestinal epithelial cells is accompanied by specific histone H3 acetylation and methylation changes

BACKGROUND: The release of LPS by bacteria stimulates both immune and specific epithelial cell types to release inflammatory mediators. It is known that LPS induces the release of IL-8 by intestinal mucosal cells. Because it is now emerging that bacteria may induce alteration of epigenetic patterns...

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Detalles Bibliográficos
Autores principales: Angrisano, Tiziana, Pero, Raffaela, Peluso, Silvia, Keller, Simona, Sacchetti, Silvana, Bruni, Carmelo B, Chiariotti, Lorenzo, Lembo, Francesca
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893597/
https://www.ncbi.nlm.nih.gov/pubmed/20546607
http://dx.doi.org/10.1186/1471-2180-10-172