Ubr1 and Ubr2 Function in a Quality Control Pathway for Degradation of Unfolded Cytosolic Proteins

Quality control systems facilitate polypeptide folding and degradation to maintain protein homeostasis. Molecular chaperones promote folding, whereas the ubiquitin/proteasome system mediates degradation. We show here that Saccharomyces cerevisiae Ubr1 and Ubr2 ubiquitin ligases promote degradation o...

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Detalles Bibliográficos
Autores principales: Nillegoda, Nadinath B., Theodoraki, Maria A., Mandal, Atin K., Mayo, Katie J., Ren, Hong Yu, Sultana, Rasheda, Wu, Kenneth, Johnson, Jill, Cyr, Douglas M., Caplan, Avrom J.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893976/
https://www.ncbi.nlm.nih.gov/pubmed/20462952
http://dx.doi.org/10.1091/mbc.E10-02-0098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893976/
https://www.ncbi.nlm.nih.gov/pubmed/20462952
http://dx.doi.org/10.1091/mbc.E10-02-0098

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