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A Nucleus-based Quality Control Mechanism for Cytosolic Proteins

Intracellular quality control systems monitor protein conformational states. Irreversibly misfolded proteins are cleared through specialized degradation pathways. Their importance is underscored by numerous pathologies caused by aberrant proteins. In the cytosol, where most proteins are synthesized,...

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Detalles Bibliográficos
Autores principales: Prasad, Rupali, Kawaguchi, Shinichi, Ng, Davis T.W.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893977/
https://www.ncbi.nlm.nih.gov/pubmed/20462951
http://dx.doi.org/10.1091/mbc.E10-02-0111