Rapid Lytic Granule Convergence to the MTOC in Natural Killer Cells Is Dependent on Dynein But Not Cytolytic Commitment

Natural killer cells are lymphocytes specialized to participate in host defense through their innate ability to mediate cytotoxicity by secreting the contents of preformed secretory lysosomes (lytic granules) directly onto a target cell. This form of directed secretion requires the formation of an i...

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Detalles Bibliográficos
Autores principales: Mentlik, Ashley N., Sanborn, Keri B., Holzbaur, Erika L., Orange, Jordan S.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893988/
https://www.ncbi.nlm.nih.gov/pubmed/20444980
http://dx.doi.org/10.1091/mbc.E09-11-0930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893988/
https://www.ncbi.nlm.nih.gov/pubmed/20444980
http://dx.doi.org/10.1091/mbc.E09-11-0930

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