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Distinct Contributions of Conserved Modules to Runt Transcription Factor Activity

Runx proteins play vital roles in regulating transcription in numerous developmental pathways throughout the animal kingdom. Two Runx protein hallmarks are the DNA-binding Runt domain and a C-terminal VWRPY motif that mediates interaction with TLE/Gro corepressor proteins. A phylogenetic analysis of...

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Detalles Bibliográficos
Autores principales: Walrad, Pegine B., Hang, Saiyu, Joseph, Genevieve S., Salas, Julia, Gergen, J. Peter
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893994/
https://www.ncbi.nlm.nih.gov/pubmed/20462957
http://dx.doi.org/10.1091/mbc.E09-11-0953