Combined effect of regulatory polymorphisms on transcription of UGT1A1 as a cause of Gilbert syndrome

BACKGROUND: Gilbert syndrome is caused by defects in bilirubin UDP-glucuronosyltransferase (UGT1A1). The most common variation believed to be involved is A(TA)7TAA. Although several polymorphisms have been found to link with A(TA)7TAA, the combined effect of regulatory polymorphisms in the developme...

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Detalles Bibliográficos
Autores principales: Matsui, Katsuyuki, Maruo, Yoshihiro, Sato, Hiroshi, Takeuchi, Yoshihiro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894006/
https://www.ncbi.nlm.nih.gov/pubmed/20529348
http://dx.doi.org/10.1186/1471-230X-10-57

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894006/
https://www.ncbi.nlm.nih.gov/pubmed/20529348
http://dx.doi.org/10.1186/1471-230X-10-57

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