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Human immunodeficiency virus type 1 Vpr: oligomerization is an essential feature for its incorporation into virus particles

HIV-1 Vpr, a nonstructural viral protein associated with virus particles, has a positive role in the efficient transport of PIC into the nucleus of non-dividing target cells and enhances virus replication in primary T cells. Vpr is a 96 amino acid protein and the structure by NMR shows three helical...

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Detalles Bibliográficos
Autores principales: Venkatachari, Narasimhan J, Walker, Leah A, Tastan, Oznur, Le, Thien, Dempsey, Timothy M, Li, Yaming, Yanamala, Naveena, Srinivasan, Alagarsamy, Klein-Seetharaman, Judith, Montelaro, Ronald C, Ayyavoo, Velpandi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894018/
https://www.ncbi.nlm.nih.gov/pubmed/20529298
http://dx.doi.org/10.1186/1743-422X-7-119