TumorBoost: Normalization of allele-specific tumor copy numbers from a single pair of tumor-normal genotyping microarrays

BACKGROUND: High-throughput genotyping microarrays assess both total DNA copy number and allelic composition, which makes them a tool of choice for copy number studies in cancer, including total copy number and loss of heterozygosity (LOH) analyses. Even after state of the art preprocessing methods,...

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Detalles Bibliográficos
Autores principales: Bengtsson, Henrik, Neuvial, Pierre, Speed, Terence P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Methodology article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894037/
https://www.ncbi.nlm.nih.gov/pubmed/20462408
http://dx.doi.org/10.1186/1471-2105-11-245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894037/
https://www.ncbi.nlm.nih.gov/pubmed/20462408
http://dx.doi.org/10.1186/1471-2105-11-245

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