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Conserved residue clusters at protein-protein interfaces and their use in binding site identification
BACKGROUND: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of structural co-operativity between spatially neighboring residues and it has previously been shown that conserved residues o...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894039/ https://www.ncbi.nlm.nih.gov/pubmed/20507585 http://dx.doi.org/10.1186/1471-2105-11-286 |