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Effect of pH on the Interaction of Gold Nanoparticles with DNA and Application in the Detection of Human p53 Gene Mutation

Gold nanoparticles (GNPs) are widely used to detect DNA. We studied the effect of pH on the assembly/disassembly of single-stranded DNA functionalized GNPs. Based on the different binding affinities of DNA to GNPs, we present a simple and fast way that uses HCl to drive the assembly of GNPs for dete...

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Detalles Bibliográficos
Autores principales: Sun, Liping, Zhang, Zhaowu, Wang, Shuang, Zhang, Jianfeng, Li, Hui, Ren, Lei, Weng, Jian, Zhang, Qiqing
Formato: Texto
Lenguaje:English
Publicado: Springer 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894134/
https://www.ncbi.nlm.nih.gov/pubmed/20596387
http://dx.doi.org/10.1007/s11671-008-9228-z