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The nucleoporin Nup188 controls passage of membrane proteins across the nuclear pore complex

All transport across the nuclear envelope (NE) is mediated by nuclear pore complexes (NPCs). Despite their enormous size, ∼60 MD in vertebrates, they are comprised of only ∼30 distinct proteins (nucleoporins or Nups), many of which form subcomplexes that act as building blocks for NPC assembly. One...

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Detalles Bibliográficos
Autores principales: Theerthagiri, Gandhi, Eisenhardt, Nathalie, Schwarz, Heinz, Antonin, Wolfram
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894445/
https://www.ncbi.nlm.nih.gov/pubmed/20566687
http://dx.doi.org/10.1083/jcb.200912045