Cargando…
Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability
Mitotic spindles play essential roles in chromosome congression and segregation during mitosis. Aurora A regulates spindle assembly in part via phosphorylating human TACC3 on S558, which triggers TACC3 relocalization to mitotic spindles and stabilizes microtubules (MTs). In this study, we identified...
Autores principales: | , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894451/ https://www.ncbi.nlm.nih.gov/pubmed/20566684 http://dx.doi.org/10.1083/jcb.200911120 |