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Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability

Mitotic spindles play essential roles in chromosome congression and segregation during mitosis. Aurora A regulates spindle assembly in part via phosphorylating human TACC3 on S558, which triggers TACC3 relocalization to mitotic spindles and stabilizes microtubules (MTs). In this study, we identified...

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Detalles Bibliográficos
Autores principales: Lin, Chiou-Hong, Hu, Chi-Kuo, Shih, Hsiu-Ming
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894451/
https://www.ncbi.nlm.nih.gov/pubmed/20566684
http://dx.doi.org/10.1083/jcb.200911120