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A cation counterflux supports lysosomal acidification

The profound luminal acidification essential for the degradative function of lysosomes requires a counter-ion flux to dissipate an opposing voltage that would prohibit proton accumulation. It has generally been assumed that a parallel anion influx is the main or only counter-ion transport that enabl...

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Detalles Bibliográficos
Autores principales: Steinberg, Benjamin E., Huynh, Kassidy K., Brodovitch, Alexandre, Jabs, Sabrina, Stauber, Tobias, Jentsch, Thomas J., Grinstein, Sergio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894458/
https://www.ncbi.nlm.nih.gov/pubmed/20566682
http://dx.doi.org/10.1083/jcb.200911083