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Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology

Motivation: The accuracy of reference genomes is important for downstream analysis but a low error rate requires expensive manual interrogation of the sequence. Here, we describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequenci...

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Detalles Bibliográficos
Autores principales: Otto, Thomas D., Sanders, Mandy, Berriman, Matthew, Newbold, Chris
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894513/
https://www.ncbi.nlm.nih.gov/pubmed/20562415
http://dx.doi.org/10.1093/bioinformatics/btq269