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Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology
Motivation: The accuracy of reference genomes is important for downstream analysis but a low error rate requires expensive manual interrogation of the sequence. Here, we describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequenci...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894513/ https://www.ncbi.nlm.nih.gov/pubmed/20562415 http://dx.doi.org/10.1093/bioinformatics/btq269 |