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The two C-terminal tyrosines stabilize occluded Na/K pump conformations containing Na or K ions

Interactions of the three transported Na ions with the Na/K pump remain incompletely understood. Na/K pump crystal structures show that the extended C terminus of the Na,K–adenosine triphosphatase (ATPase) α subunit directly contacts transmembrane helices. Deletion of the last five residues (KETYY i...

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Detalles Bibliográficos
Autores principales: Vedovato, Natascia, Gadsby, David C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894553/
https://www.ncbi.nlm.nih.gov/pubmed/20548052
http://dx.doi.org/10.1085/jgp.201010407