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The ERα coactivator, HER4/4ICD, regulates progesterone receptor expression in normal and malignant breast epithelium

The HER4 intracellular domain (4ICD) is a potent estrogen receptor (ERα) coactivator with activities in breast cancer and the developing mammary gland that appear to overlap with progesterone receptor (PgR). In fact, 4ICD has recently emerged as an important regulator and predictor of tamoxifen resp...

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Detalles Bibliográficos
Autores principales: Rokicki, Jerzy, Das, Partha M, Giltnane, Jennifer M, Wansbury, Olivia, Rimm, David L, Howard, Beatrice A, Jones, Frank E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894764/
https://www.ncbi.nlm.nih.gov/pubmed/20550710
http://dx.doi.org/10.1186/1476-4598-9-150