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The ERα coactivator, HER4/4ICD, regulates progesterone receptor expression in normal and malignant breast epithelium
The HER4 intracellular domain (4ICD) is a potent estrogen receptor (ERα) coactivator with activities in breast cancer and the developing mammary gland that appear to overlap with progesterone receptor (PgR). In fact, 4ICD has recently emerged as an important regulator and predictor of tamoxifen resp...
Autores principales: | Rokicki, Jerzy, Das, Partha M, Giltnane, Jennifer M, Wansbury, Olivia, Rimm, David L, Howard, Beatrice A, Jones, Frank E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894764/ https://www.ncbi.nlm.nih.gov/pubmed/20550710 http://dx.doi.org/10.1186/1476-4598-9-150 |
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