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No association between variation in the NR4A1 gene locus and metabolic traits in white subjects at increased risk for type 2 diabetes
BACKGROUND: The nuclear receptor NR4A1 is implicated in metabolic regulation in insulin-sensitive tissues, such as liver, adipose tissue, and skeletal muscle. Functional loss of NR4A1 results in insulin resistance and enhanced intramuscular and hepatic lipid content. Therefore, we investigated in a...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894787/ https://www.ncbi.nlm.nih.gov/pubmed/20525362 http://dx.doi.org/10.1186/1471-2350-11-84 |