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No association between variation in the NR4A1 gene locus and metabolic traits in white subjects at increased risk for type 2 diabetes

BACKGROUND: The nuclear receptor NR4A1 is implicated in metabolic regulation in insulin-sensitive tissues, such as liver, adipose tissue, and skeletal muscle. Functional loss of NR4A1 results in insulin resistance and enhanced intramuscular and hepatic lipid content. Therefore, we investigated in a...

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Detalles Bibliográficos
Autores principales:	Müssig, Karsten, Machicao, Fausto, Machann, Jürgen, Schick, Fritz, Claussen, Claus D, Stefan, Norbert, Fritsche, Andreas, Häring, Hans-Ulrich, Staiger, Harald
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894787/ https://www.ncbi.nlm.nih.gov/pubmed/20525362 http://dx.doi.org/10.1186/1471-2350-11-84

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