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Copy number variation and cytidine analogue cytotoxicity: A genome-wide association approach

BACKGROUND: The human genome displays extensive copy-number variation (CNV). Recent discoveries have shown that large segments of DNA, ranging in size from hundreds to thousands of nucleotides, are either deleted or duplicated. This CNV may encompass genes, leading to a change in phenotype, includin...

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Detalles Bibliográficos
Autores principales: Kalari, Krishna R, Hebbring, Scott J, Chai, High Seng, Li, Liang, Kocher, Jean-Pierre A, Wang, Liewei, Weinshilboum, Richard M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894803/
https://www.ncbi.nlm.nih.gov/pubmed/20525348
http://dx.doi.org/10.1186/1471-2164-11-357