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Copy number variation and cytidine analogue cytotoxicity: A genome-wide association approach
BACKGROUND: The human genome displays extensive copy-number variation (CNV). Recent discoveries have shown that large segments of DNA, ranging in size from hundreds to thousands of nucleotides, are either deleted or duplicated. This CNV may encompass genes, leading to a change in phenotype, includin...
Autores principales: | Kalari, Krishna R, Hebbring, Scott J, Chai, High Seng, Li, Liang, Kocher, Jean-Pierre A, Wang, Liewei, Weinshilboum, Richard M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894803/ https://www.ncbi.nlm.nih.gov/pubmed/20525348 http://dx.doi.org/10.1186/1471-2164-11-357 |
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