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Inhibition of StearoylCoA Desaturase Activity Blocks Cell Cycle Progression and Induces Programmed Cell Death in Lung Cancer Cells

Lung cancer is the most frequent form of cancer. The survival rate for patients with metastatic lung cancer is ∼5%, hence alternative therapeutic strategies to treat this disease are critically needed. Recent studies suggest that lipid biosynthetic pathways, particularly fatty acid synthesis and des...

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Detalles Bibliográficos
Autores principales: Hess, Daniel, Chisholm, Jeffrey W., Igal, R. Ariel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894866/
https://www.ncbi.nlm.nih.gov/pubmed/20613975
http://dx.doi.org/10.1371/journal.pone.0011394