NAD(P)H Quinone Oxidoreductase Protects TAp63γ from Proteasomal Degradation and Regulates TAp63γ-Dependent Growth Arrest

BACKGROUND: p63 is a member of the p53 transcription factor family. p63 is expressed from two promoters resulting in proteins with opposite functions: the transcriptionally active TAp63 and the dominant-negative ΔNp63. Similar to p53, the TAp63 isoforms induce cell cycle arrest and apoptosis. The ΔN...

Descripción completa

Detalles Bibliográficos
Autores principales: Hershkovitz Rokah, Oshrat, Shpilberg, Ofer, Granot, Galit
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894944/
https://www.ncbi.nlm.nih.gov/pubmed/20613985
http://dx.doi.org/10.1371/journal.pone.0011401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894944/
https://www.ncbi.nlm.nih.gov/pubmed/20613985
http://dx.doi.org/10.1371/journal.pone.0011401

Ejemplares similares