Enhanced neuronal RNAi in C. elegans using SID-1

We expressed SID-1, a transmembrane protein from Caenorhabditis elegans that is required for systemic RNAi, in C. elegans neurons. This expression increased the response of neurons to dsRNA delivered by feeding. Mutations in the lin-15b and lin-35 genes further enhanced this effect. Worms expressing...

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Detalles Bibliográficos
Autores principales: Calixto, Andrea, Chelur, Dattananda, Topalidou, Irini, Chen, Xiaoyin, Chalfie, Martin
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894993/
https://www.ncbi.nlm.nih.gov/pubmed/20512143
http://dx.doi.org/10.1038/nmeth.1463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894993/
https://www.ncbi.nlm.nih.gov/pubmed/20512143
http://dx.doi.org/10.1038/nmeth.1463

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